It's a six pointer at the top of the Premier League with tabletoppers Chelsea taking on Arsenal at Stamford Bridge.
Third placed Arsenal are four points from the lead and cannot afford to allow the Blues open up a seven point gap albeit with a game in hand.
Chelsea will be on a high after qualifying for the quarter finals of the Champions League where they got a favourable draw.
While Arsenal must follow up their victory in the North London derby with another high octane display.
Chelsea against Arsenal is the early kick off at 12.45.
Man City should follow up their composed win at Hull with another three points at home to Fulham and keep up the pressure on the top three.
Liverpool must keep showing consistency but face a tricky game in Wales against a Cardiff City side fighting for their lives at the bottom.
Man U face into life without Robin van Persie as they travel to West Ham Utd who'll be smelling blood against the fragile Red Devils.
Everton bring Swansea City to Goodison Park, Norwich City are at home to Sunderland, West Brom make the trip to Hull City and it's Newcastle Utd against Crystal Palace at St James' Park.
In the Scottish Premiership Celtic are in action against St Mirren at Parkhead.
And in the League of Ireland it's St Pats against Limerick with a 3.15 kick off at Richmond Park and Sligo Rovers meet Dundalk at the Showgrounds with a 7.45 start.
