With the top four not in League action, it's all about the battle at the bottom of the Premier League.
And it doesn't come much bigger than the meeting of Fulham and Norwich City at Craven Cottage.
Norwich have just sacked manager Chris Hughton - appointing Neil Adams till the end of the season - and are just above the relegation zone five points off the third from bottom Fulham.
So it's all or bust for the Cottagers who are 100 per cent aware this is a must win game.
There are some mismatches and two of them involve the bottom two teams.
Rockbottom Sunderland bring Everton - still harbouring ambitions of a Champions League spot - to the Stadium of Light while struggling Cardiff City make the trip to Southampton.
While fifth from bottom West Brom are at home to Spurs.
An in form Stoke City must be fancied against Newcastle Utd and it's Crystal Palace against Aston Villa at Selhurst Park.
All matches kick off at 3.07 in honour of the 25th anniversary of the Hillsborough disaster.
The first of the FA Cup semis features Arsenal against Hull City with a 5.07 start at Wembley.
Up in Scotland Rangers meet Dundee Utd in a Cup semi final at Ibrox.
