Leinster will roll out the Tullow Tank for the first time since mid-December when they take on Scarlets in Parc y Scarlets tomorrow night (k/o: 19:35).
The original Guinness PRO14 fixture had to be postponed last weekend due to the severe weather conditions forcing the closure of Dublin Airport.
Sean O'Brien has been sidelined since the European Champions Cup win in Dublin with a hip problem.
The Carlow man will captain the team on his 115th appearance for the Blues and is joined in the back row by Josh Murphy and by Jack Conan.
In the front five, Ed and Bryan Byrne again start together with Michael Bent at tighthead prop, while behind them Ross Molony is joined by Scott Fardy.
Dave Kearney lines out at full back with Barry Daly on the right wing and James Lowe on the left.
Noel Reid and Rory O'Loughlin team up in the centre while the half-backs pairing is Nick McCarthy at scrum-half and Ross Byrne in the ten shirt.
On the bench Leinster Academy scrumhalf Charlie Rock is in line to make his first appearance of the season.
Leinser Rugby (caps in brackets):
15. Dave Kearney (120)
14. Barry Daly (21)
13. Rory O'Loughlin (35)
12. Noel Reid (96)
11. James Lowe (7)
10. Ross Byrne (43)
9. Nick McCarthy (20)
1. Ed Byrne (20)
2. Bryan Byrne (24)
3. Michael Bent (102)
4. Ross Molony (58)
5. Scott Fardy (15)
6. Josh Murphy (6)
7. Seán O'Brien (114) CAPTAIN
8. Jack Conan (67)
16. James Tracy (56)
17. Peter Dooley (45)
18. Adam Coyle (1)
19. Mick Kearney (31)
20. Max Deegan (14)
21. Charlie Rock (1)
22. Ciarán Frawley (2)
23. Adam Byrne (33)