The newly released European School Survey Project on Alcohol and Other Drugs for 2019 has looked into the prevalence of drug and alcohol use and gambling among school students.
Almost 100 thousand students were surveyed across 35 countries, including nearly 2 thousand in Ireland.
It found that out of the 20 per cent of 15 and 16 year olds who've used drugs in their lifetime, 19% have used cannabis, with 3% using cocaine.
Across the board, drug-use is more common among boys than girls - with a 25% versus 15% divide in Ireland.
37% of those surveyed have used an e-cigarette in their lifetime, compared with 31% who've smoked a cigarette.
Meanwhile 72% say they have drank alcohol.
Out of the 15 and 16 year olds who said they used cannabis in the last 12 months, 5 point 7 per cent are classified as high-risk users.
The study also looked at the perceived availability of drugs - with Ireland and Denmark ranking the highest for cocaine - while cider accounts for a third to a quarter of all alcohol drank.
Just under a quarter said they gambled in the last year, with 1 in 10 of those classified as doing so excessively.