The Tanaiste says restrictions on home visits in Dublin is an option that will have to be considered.
A ban on visiting other people's residences could be introduced in the capital, as well as Limerick, as Covid-19 cases rise.
The National Public Health Emergency Team has urged people living in the two counties to reduce their social contacts.
307 new infections were confirmed yesterday, 182 of which were in Dublin while 19 were in Limerick.
The majority of cases in the capital in recent weeks have been linked with outbreaks in the home rather than social or work settings.
A restriction on visiting the homes of family and friends was recently introduced in Glasgow. Leo Varadkar says a similar measure could be brought in here;
"They took a decision, rather than closing schools again or closing childcare again and closing businesses again, that they would go really hard on gatherings within the home. That is an option that I think we'll have to consider" he said.
The Tanaiste went on to say; "what I don't know is and what I would be interested to know from the experts is has that been effective in Glasgow."
Public health warning
Dr. Ronan Glynn, Acting Chief Medical Officer, said last night that of the new infections in the capital 44 were associated with community transmission, which means there is no clear source of origin.
"I urge everyone to follow the public health advice and keep your distance. Do not underestimate the risks associated with any of your interactions, including with your family, friends or work colleagues" he said.
"Now is not a time to let down your guard – assume that you or those that you meet may be infectious and act accordingly."