Basle have been the thorn in the side for Man U and Spurs in recent years and now Chelsea can be added to the list.
The Swiss side came from behind to beat the Blues 2-1 at Stamford Bridge.
Oscar had given Chelsea the lead but Salah and Streller won it for the Swiss.
Schalke beat Steaua Bucharest 3-0.
There was another fabulous away win for Arsenal who won 2-1 at Marseille.
Theo Walcott and Aaron Ramsey shot the Gunners into an unassailable lead before there was a late consolation for the French side.
Napoli beat ten man Borussia Dortmund 2-1.
Atletico Madrid beat Zenit St Petersburg 3-1 and Porto won 1-0 at Austria Vienna.