Up to 450 jobs are to be lost or relocated from Dublin as part of plans from Deutsche Bank.
The company which has had offices in Ireland since 1991 has announce it's restructuring its operations here.
250 roles will be moved from the capital to other parts of the world, which the firm says will help simplify it's banking operations.
It will also cuts its contractor workforce.
There are around 200 people employed as contractors in Ireland, bring the total job losses announced to up to 450.
Following these changes, the Bank say there will be 200 employees still in Dublin.
Deutsche Bank say a further 35 new front office roles will be added over the summer.